In a study published in the March issue of the journal Cell Metabolism, researchers found that when a person is not actively sudden physical activity exercise. The results are within minutes of activity can result in quite rapid changes in their DNA.
Research also shows that caffeine in coffee drink every morning, can cause similar changes in the DNA. Both of these factors, exercise and caffeine, an effect equally well on men and women.
The researchers said the genetic code that underlies the formation of human muscle will not change with exercise. But the DNA molecule in the muscles will change chemically and structurally.
Change (modification) of DNA at a particular location would have an impact on determining the genetic reprogramming of muscle strength, and ultimately affect the structural and metabolic benefits of exercise.
"Our muscles really flexible," said Juleen Zierath, Karolinska Institutet researchers of women in Sweden. "Muscles adapt to what you are doing. If you do not use it, you'll lose (muscle function) it."
Zierath said, changes in DNA known as epigenetic modifications, involving the loss or increase in the four nitrogenous bases making up DNA, namely Adenine (As), Guanine (Gs), Thymine (Ts), and Cytosine (Cs).
Recent studies show DNA in the muscle men who completed exercise contains elements of chemistry, in particular methyl groups, in much smaller amounts than before exercise. Change occurs because there is stretching on the importance of gene-activating DNA that makes the muscles adapt to exercise.
In the laboratory, Zierath and her colleagues examined the effect of exercise and caffeine on muscle cell DNA. Kala is conditioned to the contraction of muscle cells, they found there was a missing section of DNA, the methyl group. Muscle cells through the same thing when given caffeine. From these findings, they concluded that caffeine gives the same effect as muscle contraction as people exercise.
In general, Zierath research provides more evidence that the human genome is much more dynamic than previously thought. Epigenetic modifications can activate a gene in a flexible. This mechanism allows the DNA in the cells of the human body adapts to environmental changes.
"Exercise is medicine," says Zierath, describes the proven benefits of exercise can transform the human genome to be more healthy.
Then, what about the people who do not have the time or not too fond of exercise? "For those who are not accustomed to exercise, consume food or beverages that contain caffeine can provide the same benefits."
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